MHY 1485
MHY1485
CAS: 326914-06-1
Molecular Formula: C17H21N7O4
MHY 1485 - Names and Identifiers
MHY 1485 - Physico-chemical Properties
| Molecular Formula | C17H21N7O4 |
| Molar Mass | 387.39 |
| Density | 1.415±0.06 g/cm3(Predicted) |
| Melting Point | 256-259 °C |
| Boling Point | 643.3±65.0 °C(Predicted) |
| Solubility | DMSO: soluble2mg/mL, clear (warmed) |
| Appearance | powder |
| Color | white to beige |
| pKa | 6.19±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months. |
| In vitro study | MHY1485 inhibits basal cell autophagic flux. MHY1485 can cause the aggregation of LC3II and the expansion of autophagosome, and its effect is dose-and time-dependent. MHY1485 can increase the level of phosphorylated mTOR and the phosphorylation of downstream S6K1 and rpS6 proteins, but does not affect the total amount of mTOR and the levels of total S6K1 and rpS6. Xenotransplantation of ovaries after short-term treatment with MHY1485 promotes secondary hair follicle growth. Transplantation after MHY1485 treatment can promote the production of mature oocytes and produce healthy offspring. |
MHY 1485 - Risk and Safety
| WGK Germany | 3 |
MHY 1485 - Reference
| Reference Show more | Note: part of our products can only provide part of the information, our company does not guarantee the authority of the information provided, only for the customer reference Exchange research. storage conditions: -20 °c solubility: DMSO MHY1485 is a mTOR activator; inhibit the auto-proliferation process by inhibition of fusion between autophagosomes and lysomes leading to the accumulation of LC3II protein and encapsulated auto-phagosomes. |
MHY 1485 - Reference Information
| biological activity | MHY1485 is an effective, cell-permeable mTOR agonist and can also effectively inhibit autophagy. |
| Target | Value |
| Animal Model: | 4-week-old female ICR mice |
| Dosage: | 10 mg/kg, 2 days |
| Administration: | Intraperitoneal injection |
| Result: | Suppressed the autophagy level following FSH treatment. |
Last Update：2024-04-09 19:05:12
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Spot supply
Product Name: MHY1485 Visit Supplier Webpage Request for quotationCAS: 326914-06-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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